Narrated by the unknown, omniscient blogger "Gossip Girl", the series revolves around the lives of privileged upper-class adolescents living in Manhattan's Upper East Side (UES). The series begins with the return of Upper East Side teenage "it girl" Serena van der Woodsen from a mysterious absence. She is reunited with her popular frenemy Blair Waldorf (Leighton Meester) and her mother Lily, and she also meets Dan Humphrey, an aspiring writer from Brooklyn who is one of Serena's main love interests throughout the show.

Main characters

Serena van der Woodsen

Blair Waldorf

Chuck Bass

Nate Archibald

Dan Humphrey

Jenny Humphrey

Vanessa Abrams

Dorota Kishlovsky

Eric Van der Woodsen